Leishmaniasis Direct Agglutination Test: Using Pictorials as Training Materials to Reduce Inter-Reader Variability and Improve Accuracy
نویسندگان
چکیده
منابع مشابه
Leishmaniasis Direct Agglutination Test: Using Pictorials as Training Materials to Reduce Inter-Reader Variability and Improve Accuracy
BACKGROUND The Direct Agglutination Test (DAT) has a high diagnostic accuracy and remains, in some geographical areas, part of the diagnostic algorithm for Visceral Leishmaniasis (VL). However, subjective interpretation of results introduces potential for inter-reader variation. We report an assessment of inter-laboratory agreement and propose a pictorial-based approach to standardize reading o...
متن کاملMethod for diagnosis of Mediterranean visceral leishmaniasis and Direct agglutination and indirect immunofluorescent antibody test
The objectives of this study were to compare the sensitivities and reliabilities of direct agglutination test (DAT), indirect immunofluorescent antibody test (IFAT), polymerase chain reaction (PCR) and bone marrow aspiration for the diagnosis of Mediterranean visceral leishmaniasis (MVL) using blood samples. Blood samples were collected from 67 confirmed MVL patients and 47 patients with other ...
متن کاملMulti-centre evaluation of repeatability and reproducibility of the direct agglutination test for visceral leishmaniasis.
OBJECTIVE To evaluate the repeatability and reproducibility of the serological direct agglutination test (DAT) for visceral leishmaniasis (VL) with aqueous antigen in a multi-centre study in VL-endemic areas in Sudan, Kenya and Nepal. METHODS Repeatability within each centre and reproducibility between the centres' results and an external reference laboratory (Belgium) was assessed on 1596 tr...
متن کاملSeroepidemiological study of visceral Leishmaniasis (human infection) in East Myankooh area, in Lorestan Province by Direct Agglutination Test (DAT)
Background: Leishmaniasis is an infection caused by a protozoan of the genus Leishmania. This descriptive and cross-sectional study was done in order to determine the seroepidemiology of visceral leishmaniasis in East Myankooh area, in Lorestan Province during 2004 – 2005 time period. Materials and methods: This study was a descriptive, cross-sectional study. Multi stage sampling was performed...
متن کاملThe direct agglutination test as an alternative method for the diagnosis of canine and human visceral leishmaniasis.
INTRODUCTION Visceral leishmaniasis is the most severe clinical form of leishmaniasis and is often fatal without proper treatment. Therefore, early and accurate diagnosis is important, but often difficult in endemic areas. OBJECTIVE The aim was to evaluate a direct agglutination test as a potential visceral leishmaniasis diagnostic method in endemic areas of Venezuela. MATERIALS AND METHODS...
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ژورنال
عنوان ژورنال: PLoS Neglected Tropical Diseases
سال: 2012
ISSN: 1935-2735
DOI: 10.1371/journal.pntd.0001946